Dr Daniel Murphy is GP Principal at Honiton Surgery in Devon, Medical Advisor to NASS, as well as a Staff Grade Rheumatologist at Royal Devon & Exeter Hospital.
Daniel provides an overview of the importance of improved diagnosis in axial SpA, in addition to providing tips for recognising axial SpA in general practice.
Axial SpA is a rare cause of a common problem: chronic back pain. As GPs, we are experts at assessing problems quickly, and picking out those key symptoms to make an efficient management plan. The first tip is listen to your intuition: Is there an alarm bell to suggest that the back pain doesn’t seem mechanical? And if that’s the case, ask more questions to determine if axial SpA could be the cause.
If a patient answers yes to 4 or more of the following 5 questions, they have an approximately 80% chance of having inflammatory back pain.
Axial SpA is associated with a range of extra-articular manifestations, or EAMs, including acute anterior uveitis, psoriasis, and inflammatory bowel disease (ulcerative colitis and Crohn’s disease). Dactylitis and enthesitis are also EAMs of axial SpA. Presence or prior bouts/ history of these conditions could indicate that a patient’s back pain is more likely to be inflammatory or axial SpA related. A family history of the above conditions, or of spondyloarthritis specifically, should also be considered.
Although the presence of EAMs can raise clinical suspicion of axial SpA, even without the presence of EAMs, presence of inflammatory back pain should indicate direct referral to rheumatology, to ensure the best outcome and treatment for patients.


For information, advice and to join a community of people who live with the condition visit the NASS website. Or visit our helpline.
Copyright ©2026 NASS. All Rights Reserved. NASS is a registered charity in England and Wales (1183175) and Scotland (SC049746)
Site by GIANT and Quickfire Digital