High prevalence of hidradenitis suppurativa symptoms in axial spondyloarthritis patients: A possible new extra-articular manifestation.
Rondags A, Arends S, Wink FR, Horváth B, Spoorenberg A. High prevalence of hidradenitis suppurativa symptoms in axial spondyloarthritis patients: A possible new extra-articular manifestation. Seminars in Arthritis and Rheumatism. 2019;48(4):611-7. https://www.sciencedirect.com/science/article/pii/S0049017218300155
Interestingly, hidradenitis suppurativa (HS) has recently also been implicated as a potential additional EAM of axial SpA. SpA and HS share several clinical and pathophysiological features, such as the association with IBD, and with elevated cytokine levels IL-17 and TNF-α. Recently, SpA was reported to be more prevalent (2.3–28.2%) in patients with HS than in the general population. The present study found that in a cohort of axial SpA patients, HS is more prevalent than in the general population (9.1% versus 0.053–4.1%). HS is associated with female gender, lower QoL, and especially higher axial SpA disease activity.