Key publications: Axial SpA in secondary care
Key publications: Axial SpA in secondary care
Extra-articular manifestations (EAMs)
Extra-articular manifestations (EAMs) are common, important features of axial spondyloarthritis (axial SpA) – the most prevalent being acute anterior uveitis (AAU), inflammatory bowel disease (IBD) and psoriasis. The pooled prevalence of AAU, psoriasis and IBD in axial SpA has previously been estimated at 16–23%, 10–11% and 4–6%, respectively1. Across the axial SpA spectrum (from non-radiographic axial SpA to radiographic axial SpA – radiographic axial SpA otherwise known as ankylosing spondylitis), the prevalence of EAMs is broadly similar. With the exception of AAU, which is slightly more prevalent in ankylosing spondylitis. EAMs contribute to the disease burden and add further complexity to the management of axial SpA2. However, they offer an excellent opportunity to pick up axial SpA early in secondary care specialities such as ophthalmology, gastroenterology and dermatology. Below, we summarise some of the key research publications discussing EAMs in axial SpA.
- de Winter JJ, van Mens LJ, van der Heijde D, Landewé R, Baeten DL. Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis. Arthritis Res Ther. 2016;18(1):196.
- Gao X, Wendling D, Botteman MF, Carter JA, Rao S, Cifaldi M. Clinical and economic burden of extra-articular manifestations in ankylosing spondylitis patients treated with anti-tumor necrosis factor agents. Journal of medical economics. 2012;15(6):1054-63.
Key EAM data sets
Key EAM data sets
Extra-articular manifestations (EAMs) are common, important features of axial spondyloarthritis (axial SpA) – the most prevalent being acute anterior uveitis (AAU), inflammatory bowel disease (IBD) and psoriasis.
We have curated resources that provide key data sets about the prevalence of EAMs.
Ophthalmology articles
Ophthalmology articles
Acute Anterior Uveitis (AAU) is the most common EAM of axial Spondyloarthritis.
Here we have curated bespoke resources setting out the prevalence of AAU, its key risk factors and screening tools to help in the awareness and identification of potential axial SpA patients for Ophthalmologists.
Dermatology articles
Dermatology articles
25% of individuals with psoriatic arthritis may also fulfil criteria for axial Spondyloarthritis.
Here we are curating bespoke resources setting out the prevalence of PSA, and screening tools to help in the awareness and identification of potential axial SpA patients for Dermatologists.
Gastroenterology articles
Gastroenterology articles
Up to 13% of individuals with IBD may have axial SpA with a high concomitance between both diseases which may help to reduce the delay in SpA diagnosis.
Here we are curating bespoke resources setting out the prevalence of axial SpA in those with IBD to help in the awareness and identification of potential axial SpA patients for Gastroenterologists.